A New Method for Database Searching: The BlastNP
نویسنده
چکیده
BLAST r © (Basic Local Alignment Search Tool) is a set of similarity search programs designed to explore all of the available sequence databases regardless of whether the query is protein or DNA. The standard nucleotide-nucleotide BLAST [blastN] has relatively low sensitivity because of the poor information density of nucleotide sequences. The standard protein-protein BLAST [blastP] is much more sensitive but the number of known real protein sequences is limited. It is possible to combine the advantages of the nucleotide and protein blasts by translating the nucleotide query [blastX], the database [TblastN] or both [TblastX] into real or conceptual protein frames.
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